Polynucleotides? Anti-aging? Firm and radiant skin? Biostimulation? Questions for PD Dr. Mathias Tremp

Face Skin
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Polynucleotides are an emerging trend in anti-ageing injections and offer an attractive alternative for skin rejuvenation and improvement of skin quality. Injections with polynucleotides not only intensively moisturize your skin, they also significantly improve its elasticity and resilience. Aesthetic treatment with polynucleotides is suitable for sensitive skin, premature skin ageing and scars, as well as for skin that is generally sagging.

What are polynucleotides?

Polynucleotides are of natural marine origin and are applied in the form of an injectable gel. They are obtained by means of a complex purification process.

As the structure of these polynucleotides differs significantly from human proteins, allergies and intolerances can be largely ruled out. They are considered bioactivators and are tiny spherical particles of a substance that also occurs in the body and are injected into and under the skin in a similar way to hyaluronic acid fillers. They increase the moisture in the skin. The skin becomes increasingly firmer and tighter in the days and weeks following treatment.

What are the benefits of using polynucleotides in anti-ageing treatments?

One advantage of polynucleotide treatment is that it boosts the body’s own processes. No foreign material is incorporated into the body, instead the skin is stimulated to carry out its own remodeling processes. Pictorially, the polynucleotides act as a signaling molecule that tells the body to renew the skin and produce collagen.

  • They can stimulate the production of collagen and elastin, which helps to improve the elasticity and firmness of the skin.
  • They can reduce the appearance of wrinkles, fine lines and sagging skin.
  • They can improve the skin’s moisture content and texture.
  • They can soothe inflammation and redness.
  • They can help to protect the skin from sun-related damage.
  • They can significantly improve acne scars and dry, calloused skin

Who is suitable for polynucleotidetreatment?

Polynucleotides are effective antioxidants and thus prevent premature skin ageing at an early stage. Treatment with polynucleotides is suitable for younger skin from the age of 30 and can be used to treat the first signs of ageing or large pores. At the same time, the overall skin structure is improved.

Biostimulators can also achieve excellent results for mature patients, sagging skin and deep wrinkles, especially in the cheek and chin area (marionette lines). The skin looks rejuvenated and fresher after just a few days. The skin structure becomes firmer, even in the area of the facial contours. This effect continues to improve over the following weeks.

Where can polynucleotides be used?

The areas of application are varied and range from the face, scalp, décolleté and neck to the sensitive skin around the eyes.

How do polynucleotides differ from conventional fillers?

Dermal fillers are usually made from a synthetic version of hyaluronic acid and act as “implants” in the skin to volumize, hydrate and improve wrinkles.

While dermal fillers can work amazingly well for some skin conditions, there are cases where a dermal filler is not the right choice and polynucleotides are more suitable. For example, many people seek a tear trough treatment for a tired, hollow eye area, but they may not be suitable for dermal fillers. This may be because the hollow is not deep enough or the skin is too thin, they have dark circles under their eyes or they have puffiness under their eyes. For these individuals, where tear trough treatment is not an option, treatment with polynucleotides may be much more suitable.

Another example would be someone who has some skin laxity (sagging skin) but does not need volume augmentation – a polynucleotide treatment would help to tighten and restore the skin without adding unnecessary volume.

What is the procedure for polynucleotide treatment?

The treatment is carried out on an outpatient basis and there is hardly any downtime. The entire treatment takes between 15 and 30 minutes, depending on the area of skin to be treated. We use extremely thin needles and the treatment is hardly painful. If desired, we can apply an anesthetic cream before the treatment. As a rule, you can resume your everyday activities immediately after the injection.

How often do I have to do the treatment?

To achieve optimal results, we recommend 4 treatments at 2-3 week intervals followed by a maintenance treatment every 3 months. Unlike dermal fillers, which provide immediate results, polynucleotide treatment requires some patience, with the best results being seen 2-3 months after treatment.

 

What do I have to consider after the treatment and what are the risks?

Polynucleotides are generally well tolerated. The main potential side effects relate to the injection site, i.e. redness, swelling and bruising. These side effects are usually mild and disappear on their own within a few days. More serious side effects, such as allergic reactions or infection, are very rare. During the pre-treatment consultation, all risks for the individual patient should be fully assessed and explained.

If necessary, you can cool your skin slightly after the treatment. Avoid sport, sauna and solarium visits for a few days. We also recommend consistent sun protection factor 50 and a moisturizing day cream (e.g. CE Ferulic from Skinceuticals).

When will I see the first results?

The results of polynucleotide treatment can be seen within a few weeks of treatment and can last for up to 12 months. The theory behind their use is that polynucleotides can interact with specific receptors on the skin cells, promoting cell regeneration and the production of new collagen and elastin fibers (biostimulation). This can lead to smoother, firmer and more youthful looking skin.

Which treatments can polynucleotides be combined with?

Which combination treatments make sense always depends on the individual skin condition and the desired effects. We often combine polynucleotide treatment with dermal fillers, wrinkle injections, botulinum treatments, radiofrequency microneedling, ultrasound treatments, peels, laser treatments or Profhilo, as combination treatments can achieve the best results.

What are the costs?

The cost of treatment is agreed in advance and starts from CHF 500. It is important to note that results can vary from person to person and the consultation is crucial to determine the best treatment options for your individual needs. Payment is made directly after treatment, preferred payment options are cash, Maestro or credit card (including Mastercard, VISA and American Express) or Postcard. Unfortunately, we do not accept payment in installments or by invoice.

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