Squamous cell carcinoma
Squamous cell carcinoma of the skin accounts for approx. 20% of all cutaneous tumors. The most important etiologic factor for the development of squamous cell carcinoma is chronic exposure to UV radiation in combination with a light skin type.
Squamous cell carcinoma of the skin usually develops on the basis of a precancerous lesion or a carcinoma in situ (actinic keratosis, leukoplakia, Bowen’s disease, erythroplasia Queyrat), but can also develop on chronically inflammatory skin (radioderm, chronic wound, chronic inflammatory skin disease) or de novo in clinically normal skin. In principle, primary lymphogenic metastases are possible, but only in about 5% of all cases.